QTM BioSciences
Your sole service partner to quantify and model subcellular drug distribution
ABOUT USGetting the actual drug concentration at the molecular target
Our services aim to contribute to a more efficient drug development process, by providing enhanced insights in a drug’s distribution profile. Thereby, we strive to make drug discovery faster and cheaper, and to prevent unnecessary human and animal studies.
To do so, we will measure the distribution of a drug within a cell. This significantly enhances insights into a drugs journey through our body, as current methods only measure a drugs distribution up to organ level.
Our Services
QUANTIFICATIONSubcellular label-free drug quantification
A drug's subcellular distribution is quantified using our proprietary in-house platform. Next, both free and bound drug concentrations in each cellular compartment are reported in a subcellular drug distribution profile.
Highly purified organelles, obtained using our proprietary purification method, are at the basis of our transport assays that can be performed as in-house service or purchased as ready-to-use assay kits.
Our AI-powered algorithms use a compounds’ physicochemical properties to simulate its distribution into the subcellular compartments and provide an estimation membrane transporter involvement.
CONSULTINGStrategic molecular PKPD consulting
Based on extensive academic and industry experience I provide strategic consultancy to support your preclinical PKPD challenges, including design and interpretation of key studies and involvement of appropriate partners.
CONTACT USQuotation Request
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