A drug's subcellular distribution is quantified using our proprietary in-house platform. Next, both free and bound drug concentrations in each cellular compartment are reported in a subcellular drug distribution profile.
Highly purified organelles, obtained using our proprietary purification method, are at the basis of our transport assays that can be performed as in-house service or purchased as ready-to-use assay kits.
Our AI-powered algorithms use a compounds’ physicochemical properties to simulate its distribution into the subcellular compartments and provide an estimation membrane transporter involvement.
Based on extensive academic and industry experience I provide strategic consultancy to support your preclinical PKPD challenges, including design and interpretation of key studies and involvement of appropriate partners.